Stem cells are a special type of cell, which can be found in almost all types of tissue and through the entire life span of multicellular organisms. Their main function is to provide tissue development, homeostasis and to repair tissue damage. Stem cells are characterised as cells that have the capacity to self renew, multipotency/pluriopotency, clonal..
Adipose-DerivedStemCells in TissueRegeneration:Review Patricia Zuk In 2001, researchers at the University of California, Los Angeles, described the isolation of a new population of adult stem cells from liposuctioned adipose tissue. These stem cells, now known as adipose-derived stem cells or ADSCs, have gone on to become one of..
Stem cells for liver tissue repair: Current knowledge and perspectives Philippe A Lysy, David Campard, Fran.oise Smets, Mustapha Najimi, Etienne M Sokal Stem cells from extra- or intrahepatic sources have been recently characterized and their usefulness for the generation of hepatocyte-like lineages has been demonstrated. Therefore, they are being incr..
Human dental pulp-derived stem cells promote locomotor recovery after complete transection of the rat spinal cord by multiple neuro-regenerative mechanisms Introduction The development of effective treatments for spinal cord injury (SCI) has been stifled by this injury’s complicated pathophysiology
Immunomodulatory properties of stem cells from human exfoliated deciduous teeth Human bone marrow mesenchymal stem cells (BMMSCs) have been identified as a population of postnatal stem cells with the potential to self-renew and differentiate into osteoblasts, chondrocytes, adipocytes, and neural cell..
TISSUE-SPECIFIC STEM CELLS MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle, ligament, tendon, and adipose. MSCs are rare in bone marrow, representing 1 in 10,000 nucleated cells. Although not immor..
Mesenchymal stem cell-mediated cancer therapy: A dual- targeted strategy of personalized medicine Xu-Yong Sun, Jiang Nong, Ke Qin, Garth L Warnock, Long-Jun Dai Cancer remains one of the leading causes of mortality and morbidity throughout the world. To a significant extent, current conventional cancer th..
Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy Massimiliano Gnecchi, Zhiping Zhang, Aiguo Ni and Victor J. Dzau Animal and preliminary human studies of adult cell therapy following acute myocardial infarction have shown an overall improvement of cardiac function. Myocardial and vascular regeneration have been initially proposed as mechanism..
